Would you consider Wikipedia as the OG open-source product? If so I think they've done a terrific job
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From the list i also prefer Hanko, the design is really nice and clean.
Also Krita is a nice open source alternative to Photoshop.
I don't want to promote my own product, but for a machine vision application, where most of the time they are too complex to keep the design simple, i think AyBorg is well designed.
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